Middlesbrough, colloquially known as Boro, is a port town in North Yorkshire, England. Lying to the south of the River Tees, Middlesbro…Middlesbrough, colloquially known as Boro, is a port town in North Yorkshire, England. Lying to the south of the River Tees, Middlesbrough forms part of the Teesside built-up area and the Tees Valley. It is located 41 miles south of Newcastle upon Tyne, 43 miles north of York, 66 miles north-west of Leeds, and 217 miles north of London. With a population of 148,215 recorded in 2021, Middlesbrough is one of the largest settlements in North East England.