Calhoun began studying mice at the Jackson Memorial Laboratory in Bar Harbor, Maine, before joining the National Institutes ...

The AI-powered home-cage monitoring solution is poised to enhance preclinical research efficiency and improve the translation of findings to clinical settings (Bar Harbor, Maine, and Allentown, N ...

Intermittent fasting has its benefits but extending living beings’ lifespan might not be one of them, according to a recent ...

A new study reveals that mice on calorie-restricted diets lived longest when they lost the least weight, challenging diet assumptions.

Risking Preclinical Toxicology Studies  Preclinical toxicology studies face a significant challenge: animal models cannot self-report side effects. This limitation proves particularly problematic when ...

POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.

Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, USA ...

Psychological stress can undermine the positive effects of calorie-restricted diets by suppressing immune function, which ...

The research, conducted by scientists at Researchers at The Jackson Laboratory (JAX), involved nearly a thousand genetically distinct mice on various dietary regimens. The study challenged ...