The Chicago White Sox are closing in on matching the 1962 New York Mets for the most losses in modern-day Major League ...

Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

The Chicago White Sox staged a two-out rally in the 9th but fell to the San Diego Padres 3-2 in 10 on Friday. The Sox are ...

Jackson Merrill will look to build on a one-hit showing in his most recent game (1-for-3 with a double and two RBI). His San ...

As the defeats continue to mount, the White Sox have joined the discussion of the most infamous baseball teams of all time.

Fernando Tatis Jr.'s run-scoring hit leading off the 10th lifted the Padres to a 3-2 victory over the White Sox Friday.

Everything you need to know about the San Diego Padres vs. Chicago White Sox game on Sept. 21, including how to watch info, ...

What unfolded Friday night at Petco Park was not a particularly well-played baseball game, which you would half-expect ...

Red Sox right-hander Richard Fitts became the second pitcher in Major League Baseball history to accomplish a feat on Friday ...

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...

Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...