Colton Cowser, James McCann and Anthony Santander led a home run parade to help the Orioles beat Detroit on Friday.

BOTTOM LINE: The Chicago White Sox, on a three-game losing streak, take on the San Diego Padres. San Diego is 43-36 in home games and 88-66 overall. The Padres have a 37-20 record in games when they ...

Manny Machado’s San Diego Padres play the Chicago White Sox on Sept. 21 at 8:40 PM ET, and will see starting pitcher Chris ...

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The Chicago White Sox are closing in on matching the 1962 New York Mets for the most losses in modern-day Major League ...

As the defeats continue to mount, the White Sox have joined the discussion of the most infamous baseball teams of all time.

Fernando Tatis Jr. wins game with double leading off the 10th inning; Joe Musgrove throws six scoreless innings ...

The San Diego Padres will don the traditional pink City Connect jerseys tonight when they host the Chicago White Sox for the first of three games at Petco Park.

It was only a matter of time before the Pirates finally reached their magic number. No, we're not talking about the one that ...

Fitts, 24, threw exactly five shutout frames against the Twins. He allowed five hits and walked one, all the while punching out three of the 21 batters he faced. The Red Sox inser ...

Everything you need to know about the San Diego Padres vs. Chicago White Sox game on Sept. 21, including how to watch info, ...