The Detroit Lions’ rebuild was jumpstarted by the fact that the first pick of the Brad Holmes and Dan Campbell, which was ...

Not surprisingly, as he prepares to take his team back to San Francisco, Lions coach Dan Campbell is still haunted by the loss.

As the 49ers look to play spoiler against the Lions on Monday Night Football, RB Isaac Guerendo got a positive injury update.

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

David Montgomery (knee) is the only player missing from the active roster. The starting running back remains in limbo, with ...

The last time Brock Purdy faced the Lions, he beat them in the NFC Championship Game. Now the Lions are coming back to town for revenge. And they're ...

The Detroit Lions and the San Francisco 49ers will go head to head for Monday Night Football this week, but tight end George ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

It's a recipe that's as versatile as it is simple. Pair it with tortilla chips, quesadillas, tacos — whatever you want on ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...